Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | We used PCR to evaluate the distribution of several of the AES-I loci amongst a collection of 188 P. aeruginosa isolates which was comprised of 35 AES-I isolates (as determined by PFGE), 78 non-AES-I CF isolates including other epidemic CF strains as well as 69 P. aeruginosa isolates from other clinical and environmental sources. | 20637114 | 2010 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | We examined the secretome of an acute, transmissible CF P. aeruginosa (Australian epidemic strain 1-R; AES-1R) compared with laboratory-adapted PAO1. | 23991618 | 2013 | ||||
|
0.090 | Biomarker | disease | BEFREE | Two clonal strains (AES-1 and AES-2) are circulating within CF centers in eastern Australia. | 17392437 | 2007 | ||||
|
0.090 | Biomarker | disease | BEFREE | Together, these properties may enhance long-term survival of AES-2 in CF lung and contribute to its transmissibility. | 19222585 | 2009 | ||||
|
0.090 | Biomarker | disease | BEFREE | The possible link between CF adults infected with AES III was attendance at family camps more than 12 years previously. | 18811887 | 2008 | ||||
|
0.090 | Biomarker | disease | BEFREE | The Australian epidemic strain-1 (AES-1) (or the Melbourne epidemic strain) and AES-2 are common in CF clinics in mainland eastern Australia, but not in the environment. | 20573059 | 2010 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | The AES-1 clone has been found to infect up to 40 % of patients in five CF centres in eastern Australia. | 19018014 | 2008 | ||||
|
0.090 | Biomarker | disease | BEFREE | Frequent clonal strains such as the Australian Epidemic Strain-1 (AES-1), have increased ability to establish infection in the CF lung and to superimpose and replace infrequent clonal strains. | 21935417 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | A genotypically indistinguishable strain of Pseudomonas aeruginosa (Australian epidemic strain III: AES III) has previously been found in a proportion of adults with cystic fibrosis (CF) in Tasmania, Australia. | 19699556 | 2009 |